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              有機化學人才網 | 最新人才 | 最新職位 | 技術交易 | 藥物合成
               
                 
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              香豆雌酚
              2010-08-20 10:44:31 來源:不詳 瀏覽:3365

              [中文名稱] 香豆雌酚

              [英文名稱] coumestrol

              [別 名] 考邁斯托醇, 擬雌內酯

              [化學名稱] 6h-benzofuro[3,2-c][1]-benzopyran-6-one, 3,9-dihydroxy-

              [分 子 式] c15h8o5;

              [分 子 量] 268.21

              [物理性質] 熔點 385°。325°升華, 在高真空下約175°升華。幾乎不溶于酸性水、中性水及石油醚, 微溶于堿性水(ph11-12), 略微溶于甲醇、氯仿及乙醚, 極微溶于四氯化碳及苯。uvλetohmax nm: 343, 304, 244; uvλetoh-naohmax nm: 3871, 320, 281, 260[1]。

              [成分分類] 黃酮、香豆素及類似物

              [藥理作用] 具有雌激素樣活性, 本品0.24mg能使小鼠子宮增重25mg, 但作用強度遠較雌酮弱, 相對強度為35:6900[5], 尚有抗生育和抗真菌作用[6,7]。

              [毒 性]

              [不良反應]

              [用 途] 性激素, 抗真菌

              [成分來源] 豆科植物紫苜蓿 medicago sativa l. 全草[2,3], ^a菊科植物^b藥用蒲公英 taraxacum officinale wigg. ^c根[4], ^b白車軸草 trifolium repens l. [3], ^b草莓車軸草 trifolium fragiferum l. [3]

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