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              2018年11月FDA批準上市新藥lorlatinib
              2018-11-04 08:34:49 來源:有機化學網 瀏覽:4888
              2018年11月2日,美國食品和藥物管理局已批準lorlatinib(Lorbrena)加速批準用于治療ALK陽性轉移性非小細胞肺癌(NSCLC)的患者,這些患者已在1種或更多種ALK酪氨酸激酶抑制劑(TKIs)上進展。

              具體而言,lorlatinib被批準用于克唑替尼(Xalkori)和至少另外1種ALK抑制劑治療轉移性疾病的患者; alectinib(Alecensa)作為第一種ALK抑制劑治療轉移性疾病; 或ceritinib(Zykadia)作為第一種ALK抑制劑治療轉移性疾病。

              CAS No.: 1454846-35-5
              Formula: C21H19FN6O2
              Exact Mass: 406.15500
              Molecular Weight: 406.41300

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