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              2015年8月FDA批準上市新藥FLIBANSERIN氟班色林-女性偉哥上市!
              2015-10-10 14:36:15 來源:有機化學網 瀏覽:120119

              2015年8月18日,FDA批準綽號“女性偉哥”的藥物氟班色林(flibanserin)上市,理由是它有助于提升女性的性欲。

              Flibanserin原為抗抑郁劑,但被發現能夠增加性欲以及提升性滿意度;不過因為安全議題,自從2010年起共被FDA退回兩次,成員相似的顧問小組,在五年前無異議否決了這項藥品。

              因為Flibanserin的副作用包含低血壓、暈眩等…再加上與酒精和其他常見藥品容易發生相互影響,恐有安全疑慮。專家表示,這種療法可能被濫用為約會迷 奸的藥物,必須提高關注。

              英文名 Flibanserin
              別名 3-[2-[4-[4-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one
              產品名稱 氟班色林; 3-[2-[4-[4-(三氟甲基)苯基]哌嗪-1-基]乙基]-1H-苯并咪唑-2-酮
              copyRight
              分子結構 CAS 登錄號:167933-07-5, 氟立班絲氨, 3-[2-[4-[4-(三氟甲基)苯基]哌嗪-1-基]乙基]-1H-苯并咪唑-2-酮
              分子式 C20H21F3N4O
              分子量 390.40
              CAS 登錄號 167933-07-5

               

              氟班色林的合成非常簡單,主要原料是對三氟甲基苯胺和鄰苯二胺,主要反應是環合和取代。原料成本非常低。

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